| Identification | Back Directory | [Name]
3-amino-3-deoxy-D-glucose hydrochloride | [CAS]
57649-10-2 | [Synonyms]
Kanosamine hydrochloride >=97.0% (TLC)
(2R,3S,4S,5R)-3-amino-2,4,5,6-tetrahydroxyhexanal:hydrochloride | [EINECS(EC#)]
260-881-4 | [Molecular Formula]
C6H13NO5.ClH | [MDL Number]
MFCD01725274 | [MOL File]
57649-10-2.mol |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
≤5mg/ml in ethanol;25mg/ml in DMSO;25mg/ml in dimethyl formamide | [form ]
crystalline solid | [color ]
White to off-white | [Stability:]
Very Hygroscopic |
| Hazard Information | Back Directory | [Description]
Kanosamine, a constituent of kanamycin, is an antibiotic produced by Streptomyces and Bacillus that can inhibit cell wall synthesis in plant-pathogenic oomycetes (MIC = 25 μg/ml for P. medicaginis M2913) and certain fungi as well as some bacterial species (MIC = 400 μg/ml for S. aureus). It has been explored as an alternative and/or supplement to synthetic pesticides and genetic resistance of crop plants for the management of plant disease. | [Uses]
An antibiotic which inhibits the growth of Saccharomyces cerevisiae and a range of human pathogenic fungi, including Candida albicans. | [storage]
Store at -20°C | [References]
[1] milner j l, silo-suh l, lee j c, et al. production of kanosamine by bacillus cereus uw85[j]. applied and environmental microbiology, 1996, 62(8): 3061-3065.
[2] dolak l a, castle t m, dietz a, et al. 3-amino-3-deoxyglucose produced by a streptomyces sp[j]. the journal of antibiotics, 1980, 33(8): 900-901.
[3] janiak a m, milewski s. mechanism of antifungal action of kanosamine[j]. medical mycology, 2001, 39(5): 401-408. |
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