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ChemicalBook--->CAS DataBase List--->5707-55-1

5707-55-1

5707-55-1 Structure

5707-55-1 Structure
IdentificationBack Directory
[Name]

2-(3,4-dihydroxyphenyl)acetaldehyde
[CAS]

5707-55-1
[Synonyms]

Dopal (>
Dopal (>80%)
3,4-Dihydroxyphenylacetaldehyde
2-(3,4-dihydroxyphenyl)acetaldehyde
Benzeneacetaldehyde, 3,4-dihydroxy-
Droxidopa Impurity 2Q: What is Droxidopa Impurity 2 Q: What is the CAS Number of Droxidopa Impurity 2 Q: What is the storage condition of Droxidopa Impurity 2 Q: What are the applications of Droxidopa Impurity 2
[Molecular Formula]

C8H8O3
[MDL Number]

MFCD19707262
[MOL File]

5707-55-1.mol
[Molecular Weight]

152.15
Chemical PropertiesBack Directory
[Boiling point ]

350.9±27.0 °C(Predicted)
[density ]

1.306±0.06 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

9.62±0.10(Predicted)
[color ]

Pale Brown to Very Dark Brown
[Stability:]

Hygroscopic
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H312-H332
[Precautionary statements ]

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501
Hazard InformationBack Directory
[Uses]

Dopal is a product of Dopamine (CAT# D533780) catabolism by monoamine oxidase and may be further oxidized to 3,?4-?Dihydroxyphenylacetic Acid (CAT# D454250) via aldehyde dehydrogenase. DOPAL can also be reduced to Hydroxy Tyrosol (CAT# H977000) via cytosolic aldehyde or aldose reductase. DOPAL is harmful to nigrostriatal DA terminals and contributes to the profound putamen DA deficiency found in Parkinson''s disease. Cytosolic and mitochondrial aldehyde dehydrogenase (ALDH) isoenzymes deficiency in mice results in increased levels of DOPAL, causing neurodegeneration and motor dysfunction also associated with Parkinson''s disease.
[Uses]

Dopal is the reactive metabolite of dopamine (D533780), an endogenous catecholamine with α and β-adrenergic activity.
[Definition]

ChEBI: A phenylacetaldehyde in which the 3 and 4 positions of the phenyl group are substituted by hydroxy groups.
[IC 50]

α-synuclein Aggregation
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