| Identification | Back Directory | [Name]
SCH 446132 | [CAS]
569351-91-3 | [Synonyms]
SCH 446132
Dasantafil
7-(3-Bromo-4-methoxybenzyl)-1-ethyl-8-(((1R,2R)-2-hydroxycyclopentyl)amino)-3-(2-hydroxyethyl)-3,7-dihydro-1H-purine-2,6-dione
1H-Purine-2,6-dione, 7-[(3-bromo-4-methoxyphenyl)methyl]-1-ethyl-3,7-dihydro-8-[[(1R,2R)-2-hydroxycyclopentyl]amino]-3-(2-hydroxyethyl)- | [Molecular Formula]
C22H28BrN5O5 | [MDL Number]
MFCD31807142 | [MOL File]
569351-91-3.mol | [Molecular Weight]
522.39 |
| Chemical Properties | Back Directory | [Boiling point ]
743.0±70.0 °C(Predicted) | [density ]
1.62±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
14.51±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
This product is Informer compound X12 of the Aryl Halide Chemistry Informer Library developed by chemists at Merck & Co., Inc., Kenilworth, NJ, U.S.., Inc., Kenilworth, NJ, U.S., which contains 18 drug-like molecules representative of those encountered in complex synthesis. By screening a new reaction against the Informer Library, chemists can directly compare and analyze a reactions′s successes and shortcomings among different methods and various research teams. It may also be used to faciliate deeper method development for performance or utility. | [Uses]
Treatment of erectile dysfunction (phosphodiesterase (PDE) 5 isoenzyme inhibitor). | [General Description]
Dasantafil (SCH-446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to in genitourinary disorders and study erectile dysfunction. |
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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