| Identification | Back Directory | [Name]
PROPENTOFYLLINE | [CAS]
55242-55-2 | [Synonyms]
hextol
hoe-285
HWA 285
karsivan
albert-285
PROPENTOFYLLINE
HOE-285：Hextol：Karsivan
1-(5-oxohexyl)-3-methyl-7-propylxanthine
3-METHYL-1-[5-OXOHEXYL]-7-PROPYL-XANTHINE
3-Methyl-1-(5-oxohexyl)-7-propylpurine-2,6-dione
3,7-dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1h-purine-6-dione
3,7-DIHYDRO-3-METHYL-1-(5-OXOHEXYL)-7-PROPYL-1H-PURINE-2,6-DIONE
1H-Purine-2,6-dione, 3,7-dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-
3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dione, HWA-285, Albert-285, HOE-285, Hextol, Karsivan
3-Methyl-1-(5-oxohexyl)-7-propylxanthine, HWA285, 3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dione | [Molecular Formula]
C15H22N4O3 | [MDL Number]
MFCD00133785 | [MOL File]
55242-55-2.mol | [Molecular Weight]
306.36 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
64-66°C | [Boiling point ]
541.4±56.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
H2O: soluble12.4mg/mL | [form ]
solid | [pka]
0.58±0.70(Predicted) | [color ]
white | [Water Solubility ]
H2O: 12.4mg/mL |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
A c-AMP phosphodiesterase inhibitor. A nerve growth factor stimulator. An adenosine transport inhibitor. A non-selective adenosine receptor antagonist. Nootropic | [Description]
Propentofylline is a nootropic indicated for cerebrovascular disorders. Other indications
currently under investigation include senile dementia, stroke and hypoxia. | [Originator]
Hoechst AG (W.Germany) | [Definition]
ChEBI: Propentofylline is an oxopurine. | [Brand name]
Hextol | [Biochem/physiol Actions]
c-AMP phosphodiesterase inhibitor; nerve growth factor stimulator; adenosine transport inhibitor; non-selective adenosine receptor antagonist. |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
20/21/22 | [WGK Germany ]
3 | [RTECS ]
UO8438700 | [Toxicity]
LD50 in male, female mice, male, female rats (mg/kg): 900, 780, 1150, 940 orally; 168, 170, 180, 195 i.v.; 375, 346, 199, 196 i.p.; 450, 508, 400, 338 s.c. (Inazu) |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
|