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ChemicalBook--->CAS DataBase List--->52580-29-7

52580-29-7

52580-29-7 Structure

52580-29-7 Structure
IdentificationBack Directory
[Name]

ASP-ARG-VAL-TYR
[CAS]

52580-29-7
[Synonyms]

DRVY
ASP-ARG-VAL-TYR
ANGIOTENSIN II (1-4)
H-Asp-Arg-Val-Tyr-OH
ANGIOTENSIN II (1-4) HUMAN
L-Tyrosine, L-α-aspartyl-L-arginyl-L-valyl-
[Molecular Formula]

C24H37N7O8
[MDL Number]

MFCD00079800
[MOL File]

52580-29-7.mol
[Molecular Weight]

551.59
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[Sequence]

H-Leu-Arg-Gln-Ser-Gln-Phe-Val-Gly-Ser-Arg-OH
Hazard InformationBack Directory
[Uses]

Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[1][2].
[storage]

Store at -20°C
[References]

[1] De Giusti VC, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. DOI:10.3389/fphys.2013.00411
[2] Moon JY, et al. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-5. DOI:10.5049/EBP.2013.11.2.41
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