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ChemicalBook--->CAS DataBase List--->51744-82-2

51744-82-2

51744-82-2 Structure

51744-82-2 Structure
IdentificationBack Directory
[Synonyms]

D-Homoserine lactone
D-Homocysteine Lactone
(3R)-3-aminooxolan-2-one
2(3H)-Furanone, 3-aminodihydro-, (3R)-
2(3H)-Furanone,3-aminodihydro-,(3R)-(9CI)
[MOL File]

51744-82-2.mol
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

A solid
[pka]

7.89±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
Hazard InformationBack Directory
[Uses]

D-Homoserine lactone is a signaling molecule with the activity of regulating bacterial quorum sensing. The chemical structure of D-Homoserine lactone makes it a potential regulator of the AHL synthase RhlI. D-Homoserine lactone has been shown to inhibit the activity of RhlI, thereby affecting the bacterial quorum sensing signaling pathway. D-Homoserine lactone is also an enantiomer of L-homoserine lactone and is used as an inhibitor of serine hydroxymethyltransferase[1].
[Definition]

ChEBI: D-homoserine lactone is the D-enantiomer of homoserine lactone. It is an enantiomer of a L-homoserine lactone.
[References]

[1] N- Acyl Homoserine Lactone Analog Modulators of the Pseudomonas aeruginosa Rhll Quorum Sensing Signal Synthase
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