| Identification | Back Directory | [Name]
RUBROPUNCTATIN | [CAS]
514-67-0 | [Synonyms]
RUBROPUNCTATIN
Rubropuncatatin
(9aR)-3-hexanoyl-9a-methyl-6-[(E)-prop-1-enyl]furo[3,2-g]isochromene-2,9-dione
(R-(E))-9A-Methyl-3-(1-oxohexyl)-6-(1-propenyl)-2H-furo(3,2-G)(2)benzopyran-2,9(9ah)-dione
(R)-9a-Methyl-3-(1-oxohexyl)-6-[(E)-1-propenyl]-2H-furo[3,2-g][2]benzopyran-2,9(9aH)-dione
2H-Furo(3,2-G)(2)benzopyran-2,9(9ah)-dione, 9A-methyl-3-(1-oxohexyl)-6-(1-propenyl)-, (R-(E))-
2H-Furo[3,2-g][2]benzopyran-2,9(9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propen-1-yl-, (9aR)- | [Molecular Formula]
C21H22O5 | [MDL Number]
MFCD34470836 | [MOL File]
514-67-0.mol | [Molecular Weight]
354.4 |
| Chemical Properties | Back Directory | [Melting point ]
156.5-157.0 °C (decomp)(Solv: ethyl ether (60-29-7)) | [Boiling point ]
638.8±55.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [form ]
Solid | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
Rubropunctatin is used in preparation Method for separating and purifying Rubropunctatin in monascus polished glutinous rice. | [in vivo]
Rubropunctatin (8-32 mg/kg; i.v. for 5 times) has anti-tumor effect mice[1].
Rubropunctamine inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, with an ID50 of 0.11 mg/ear[3]. | Animal Model: | Male nude mice (5 weeks) are inoculated with BGC-823 cells[1] | | Dosage: | 8, 32 mg/kg | | Administration: | I.v. five times (day 1st, 4th, 7th, 10th, and 13th) | | Result: | Diminished the tumor volume by 11.1% (8 mg/kg) and 24.2% (32 mg/kg).
Reduced the tumor weight by 23.5% (8 mg/kg) and 37.7% (32 mg/kg).
No significant difference was observed on the body weight.
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