| Identification | Back Directory | [Name]
Liensinine diperchlorate | [CAS]
5088-90-4 | [Synonyms]
Liensinine diperchlorate
Liensinine diperchlorate, 98%, from Nelumbo nucifera Gaertn. | [Molecular Formula]
C37H43ClN2O10 | [MDL Number]
MFCD16879086 | [MOL File]
5088-90-4.mol | [Molecular Weight]
711.21 |
| Hazard Information | Back Directory | [Uses]
Liensinine Diperchlor?ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlor?ate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlor?ate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc[1]. | [storage]
Store at -20°C | [References]
[1] Zhou J, et al. A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission. Autophagy. 2015;11(8):1259-79. DOI:10.1080/15548627.2015.1056970 |
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