| Identification | Back Directory | [Name]
anemonin | [CAS]
508-44-1 | [Synonyms]
ANEMONIN(P)
Anemonin (6CI)
Anemone camphor
Pulsatilla camphor
Anemonin/Pulsatilla camphor
1,7-dioxadispiro[4.0.4^{6}.2^{5}]dodeca-3,9-diene-2,8-dione
(5S,6S)-1,7-dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione
1,7-dioxadispiro[4.0.4^{6}.2^{5}]dodeca-3,9-diene-2,8-quinone
(5R,6R)-rel-1,7-Dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione
1,7-Dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione, (5R,6R)-rel-
(5R,6R)-4,7-dioxadispiro[4.0.4^{6}.2^{5}]dodeca-1,9-diene-3,8-dione | [Molecular Formula]
C10H8O4 | [MOL File]
508-44-1.mol | [Molecular Weight]
192.17 |
| Chemical Properties | Back Directory | [Melting point ]
157-158℃ | [Boiling point ]
248.14°C (rough estimate) | [density ]
1.45 | [refractive index ]
1.4440 (estimate) | [storage temp. ]
-20°C | [solubility ]
Insoluble Diethyl ether | [InChI]
InChI=1/C10H8O4/c11-7-1-3-9(13-7)5-6-10(9)4-2-8(12)14-10/h1-4H,5-6H2/t9-,10-/s3 | [InChIKey]
JLUQTCXCAFSSLD-DPIMBTEZNA-N | [SMILES]
O1[C@]2(CC[C@]32C=CC(=O)O3)C=CC1=O |&1:1,4,r| |
| Hazard Information | Back Directory | [Description]
Anemonin (ANE) is a natural bioactive compound, an active compound of C. crassifolia, that regulates tyrosinase-related proteins and mRNAs in human melanocytes and inhibits melanin synthesis, making it a potential cosmetic ingredient. In addition, Anemonin has anti-aging properties, and it has been shown that ANE ameliorates human diploid fibroblast 2BS and IMR90 cellular senescence via the PARP1-NAD+-SIRT1 signalling pathway. | [Uses]
Anemonin is a Chinese herbal medicinal ingredient that inhibits pigmentation synthesis in human melanocytes. | [Biological Functions]
Anemonin has anti-inflammatory effects, and its mechanism of action is to exert anti-inflammatory effects by targeting the regulation of protein kinase C-θ (PKC-θ) and inhibiting the expression of related inflammatory factors, which has the potential to treat ulcerative colitis. | [Biological Activity]
Anemonin is the dimerization product of the toxin protoanemonin and easily reacts with water to a dicarboxylic acid. | [Physiological effects]
Anemonin have the effect of antispasmodic and analgesic. |
|
| Company Name: |
cuicheng bio
|
| Tel: |
13186333400 |
| Website: |
www.cuichengbio.com/ |
|