| Identification | Back Directory | [Name]
N-(1-ANILINONAPHTHYL-4)-MALEIMIDE | [CAS]
50539-45-2 | [Synonyms]
ANM
N-(1-Anilinophenyl)maleimide
N-(1-ANILINONAPHTHYL-4)-MALEIMIDE
N-(4-ANILINO-1-NAPHTHYL)MALEIMIDE
N-(1-anilinonaphthalyl)-4-maleimide
N-(1-ANILINONAPHTHYL-4)-MALEIMIDE[ANM]
N-[4-(Phenylamino)-1-naphtyl]maleimide
N-MaleiMido-N`-phenyl-1,4-NaphthalenediaMine
1-(4-Anilino-1-naphtyl)-3-pyrroline-2,5-dione
1-[4-(phenylamino)naphthyl]-1H-pyrrole-2,5-dione
N-(4-ANILINO-1-NAPHTHYL)MALEIMIDE, FOR F LUORESCENCE
1-(4-(PHENYLAMINO)-1-NAPHTHALENYL)-1H-PYRROLE-2,5-DIONE
1-[4-(phenylamino)naphthalen-1-yl]-2,5-dihydro-1H-pyrrole-2,5-dione | [EINECS(EC#)]
256-618-8 | [Molecular Formula]
C20H14N2O2 | [MDL Number]
MFCD00042694 | [MOL File]
50539-45-2.mol | [Molecular Weight]
314.34 |
| Chemical Properties | Back Directory | [Appearance]
red powder | [Melting point ]
207 °C
| [Boiling point ]
454.02°C (rough estimate) | [density ]
1.2303 (rough estimate) | [refractive index ]
1.5700 (estimate) | [pka]
3.50±0.30(Predicted) | [CAS DataBase Reference]
50539-45-2 |
| Hazard Information | Back Directory | [Chemical Properties]
red powder | [Uses]
N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm[1]. | [References]
[1] T Honda, et al. Characterization of the reactivity of sulphydryl groups in tryptophanase by a dual-monitoring high-performance liquid chromatographic system with a site-directed fluorescent reagent. J Chromatogr. 1986 Dec 26;371:353-60. DOI:10.1016/s0021-9673(01)94718-1
[2] S Chaen, et al. Fluorescence properties and contraction characteristics of ANM (N-(1-anilinonaphthyl-4)maleimide)-labeled rabbit psoas muscle fibers. J Biochem. 1985 Oct;98(4):939-47. DOI:10.1093/oxfordjournals.jbchem.a135374 |
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