| Identification | Back Directory | [Name]
L-ProlinaMide, (2R)-2-butyl-N-forMyl-N-hydroxy-β-alanyl-N-(5-fluoro-1-oxido-2-pyridinyl)- | [CAS]
478913-91-6 | [Synonyms]
LBM415
NVP-PDF-713
(2R)-2-BUTYL-N-FORMYL-N-HYDROXY--ALANYL-N-(5-FLUORO-1-OXIDO-2-PYRIDINYL)-L-PROLINAMIDE
L-ProlinaMide, (2R)-2-butyl-N-forMyl-N-hydroxy-β-alanyl-N-(5-fluoro-1-oxido-2-pyridinyl)- | [Molecular Formula]
C18H25FN4O5 | [MDL Number]
MFCD22741896 | [MOL File]
478913-91-6.mol | [Molecular Weight]
396.41 |
| Hazard Information | Back Directory | [Uses]
LBM-415 (NVP-PDF 713) is a peptide deformylase (PDF) inhibitor that exhibits inhibitory activity against various antimicrobial-resistant gram-positive cocci, with a MIC90 range of 0.12-8 μg/ml. Additionally, inhibiting efflux pump activity can enhance bacterial sensitivity to LBM415, thereby improving its antibacterial efficacy[1]. | [References]
[1] Fritsche TR, et al. Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance. Antimicrob Agents Chemother. 2005 Apr;49(4):1468-76. DOI:10.1128/AAC.49.4.1468-1476.2005 |
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| Company Name: |
AstaTech, Inc
|
| Tel: |
(215) 785 3197 |
| Website: |
www.astatechinc.com |
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