| Chemical Properties | Back Directory | [Melting point ]
175 °C | [Boiling point ]
465.3±45.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [form ]
Solid | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Eleutherin is a type of naphthoquinone derivative with the protective effect against the injury ofhuman umbilical vein endothelial cells (HUVECs), which can be isolated from the edible bulbs of Eleutherine americana (Hong-Cong)[1]. | [Definition]
ChEBI: Eleutherin is a benzoisochromanequinone and a member of p-quinones. | [References]
[1] Chen D, et al. New naphtoquinones derivatives from the edible bulbs of Eleutherine americana and their protective effect on the injury of human umbilical vein endothelial cells. Fitoterapia. 2019 Jan;132:46-52. DOI:10.1016/j.fitote.2018.11.009
[2] Castro ALG, et, al. Evaluation of the genotoxicity and mutagenicity of isoeleutherin and eleutherin isolated from Eleutherine plicata herb. using bioassays and in silico approaches. Arabian Journal of Chemistry. Volume 14, Issue 4, April 2021, 103084.
[3] Krishnan P, et, al. Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives-eleutherin, alpha lapachone, and beta lapachone. Biochem Pharmacol. 2000 Nov 1;60(9):1367-79. DOI:10.1016/s0006-2952(00)00437-8 |
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