Identification | Back Directory | [Name]
Ritobegron ethyl hydrochloride | [CAS]
476333-91-2 | [Synonyms]
KUC7483 KUC-7483 KUC 7483 Ritobegron HCl Ritobegron hydrochloride Ritobegron ethyl hydrochloride | [Molecular Formula]
C23H32ClNO5 | [MOL File]
476333-91-2.mol | [Molecular Weight]
437.96 |
Hazard Information | Back Directory | [Uses]
Ritobegron, a prodrug of the active compound, KUC-7322, is a selective β3 -adrenoceptor agonist. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system. | [References]
[1] Maruyama I, Goi Y, Tatemichi S, et al. Bladder selectivity of the novel β?-agonist ritobegron (KUC-7483) explored by in vitro and in vivo studies in the rat. Naunyn Schmiedebergs Arch Pharmacol. 2012;385(8):845-852. DOI:10.1007/s00210-012-0755-x [2] Maruyama I, Tatemichi S, Goi Y, et al. Effects of ritobegron (KUC-7483), a novel selective β3-adrenoceptor agonist, on bladder function in cynomolgus monkey. J Pharmacol Exp Ther. 2012;342(1):163-168. DOI:10.1124/jpet.112.191783 |
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