| Identification | Back Directory | [Name]
EXO1 | [CAS]
461681-88-9 | [Synonyms]
EXO1
EOX 1
hExo1
hExoI
Exonuclease 1
EXOCYTIC INHIBITOR 1
4-FLUORO-BZ-2-ABZ-OME
2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
Anti-EXO1, N-Terminal antibody produced in rabbit
2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER
Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate | [Molecular Formula]
C15H12FNO3 | [MDL Number]
MFCD00028104 | [MOL File]
461681-88-9.mol | [Molecular Weight]
273.26 |
| Hazard Information | Back Directory | [Uses]
Exo1 is used in the synthetic preparation of tricyclic heterocyclic compounds as antagonists of tachykinin receptor (substance P receptor) for prevention and/or treatment of substance P-related diseases. | [Definition]
ChEBI: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester is a member of benzamides. | [Biological Activity]
Reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC 50 ~ 20 mM). Has similar, but not identical, action to brefeldin A (1,6,7,8,9,11ab,12,13,14,14aa-Decahydro-1b,13a-dihydroxy-6b-methyl-4H-cyclopent(f)oxacyclotridecin-4-one ). |
|
| Company Name: |
ZSGB-BIO
|
| Tel: |
02-400-810-9781 400810978 |
| Website: |
www.zsbio.com |
|