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ChemicalBook--->CAS DataBase List--->452296-83-2

452296-83-2

452296-83-2 Structure

452296-83-2 Structure
IdentificationBack Directory
[Name]

BMS 043
[CAS]

452296-83-2
[Synonyms]

BMS 043
BMS 488043
CHEMBL238103
UNII-MKS21EJ435
1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione
1-(4-Benzoyl-1-piperazinyl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-1,2-ethanedione
1,2-Ethanedione, 1-(4-benzoyl-1-piperazinyl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-
[Molecular Formula]

C22H22N4O5
[MDL Number]

MFCD18782663
[MOL File]

452296-83-2.mol
[Molecular Weight]

422.43
Chemical PropertiesBack Directory
[Melting point ]

229.5-232 °C
[Boiling point ]

672.9±65.0 °C(Predicted)
[density ]

1.363±0.06 g/cm3(Predicted)
[pka]

12.26±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

BMS 488043 (BMS 043) is an orally active and well-tolerated inhibitor of the attachment of human immunodeficiency virus type 1 (HIV-1) to CD4+ lymphocytes[1].
[References]

[1] George J Hanna, et al. Antiviral activity, pharmacokinetics, and safety of BMS-488043, a novel oral small-molecule HIV-1 attachment inhibitor, in HIV-1-infected subjects. Antimicrob Agents Chemother. 2011 Feb;55(2):722-8. DOI:10.1128/AAC.00759-10
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