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ChemicalBook--->CAS DataBase List--->451-71-8

451-71-8

451-71-8 Structure

451-71-8 Structure
IdentificationBack Directory
[Name]

Glyhexamide
[CAS]

451-71-8
[Synonyms]

Subose
Serbose
SQ-15860
NSC-106960
Glyhexamide
1-cyclohexyl-3-indan-5-ylsulfonyl-urea
1-cyclohexyl-3-(2,3-dihydro-1H-inden-5-ylsulfonyl)urea
N-[(Cyclohexylamino)carbonyl]-2,3-dihydro-1H-indene-5-sulfonamide
1H-Indene-5-sulfonamide, N-[(cyclohexylamino)carbonyl]-2,3-dihydro-
[Molecular Formula]

C16H22N2O3S
[MDL Number]

MFCD00865480
[MOL File]

451-71-8.mol
[Molecular Weight]

322.42
Chemical PropertiesBack Directory
[Melting point ]

153-155°
[density ]

1.30±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

5.28±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Glyhexamide is an effective hypoglycemic agent in adult diabetics.
[Definition]

ChEBI:Glyhexamide is a member of indanes.
[in vivo]

Glyhexamide, a new cyclic sulfonylurea, is an effective hypoglycemic agent in adult diabetics, this activity is unaccompanied by increases in serum (immunoreactive) insulin concentrations.

[storage]

Store at -20°C
[References]

[1] E. M. Gold, et al. Insulin Production in Overt (Maturity-Onset) Diabetes: Absence of Hyperinsulinemia Despite Hyperglycemia Induced by Contraceptive Steroids. Metabolic Effects of Gonadal Hormones and Contraceptive Steroids pp 144-156.
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