| Identification | Back Directory | [Name]
L-Threonine, L-α-glutamyl-L-glutaminyl-L-valyl-L-threonyl-L-asparaginyl-L-valylglycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl- | [CAS]
440645-08-9 | [Synonyms]
α-Synuclein (61-75)
L-Threonine, L-α-glutamyl-L-glutaminyl-L-valyl-L-threonyl-L-asparaginyl-L-valylglycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl- | [Molecular Formula]
C60H103N17O23 | [MOL File]
440645-08-9.mol | [Molecular Weight]
1430.58 |
| Hazard Information | Back Directory | [Uses]
α-Synuclein (61-75) is the 61-75 fragment of α-Synuclein. α-Synuclein is an abundant neuronal protein that is highly enriched in presynaptic nerve terminals. α-Synuclein is a potential biomarker for Parkinson's disease (PD)[1][2]. | [IC 50]
α-synuclein | [References]
[1] Jacqueline Burré, et al. Cell Biology and Pathophysiology of α-Synuclein. Cold Spring Harb Perspect Med. 2018 Mar 1;8(3):a024091. DOI:10.1101/cshperspect.a024091
[2] Nelson Ferreira, et al. Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain. Acta Neuropathol Commun. 2021 Feb 25;9(1):31. DOI:10.1186/s40478-021-01131-8 |
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