| Identification | Back Directory | [Name]
4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone | [CAS]
43076-30-8 | [Synonyms]
Terfenadine EP Impurity A
Terfenadine impurity A CRS
Terfenadine USP Related Compound A
4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone
1-(4-TERT-BUTYLPHENYL)-4-[4-(ALPHA-HYDROXYBENZHYDRYL)PIPERIDINO]BUTAN-1-ONE
1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one
1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one
1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-
1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one (Terfenadone) | [EINECS(EC#)]
256-074-1 | [Molecular Formula]
C32H39NO2 | [MOL File]
43076-30-8.mol | [Molecular Weight]
469.66 |
| Chemical Properties | Back Directory | [Melting point ]
175 °C | [Boiling point ]
624.5±55.0 °C(Predicted) | [density ]
1.082±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [pka]
13.32±0.29(Predicted) |
| Hazard Information | Back Directory | [Uses]
Terfenadone, is the first nonsedating antihistamine for the treatment of allergic rhinitis. It is also the derivative of Terfenadine (T114500). Terfenadine, has been also identified to be an inhibitor of human CD81-receptor HCV-E2 interaction. |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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