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ChemicalBook--->CAS DataBase List--->43042-79-1

43042-79-1

43042-79-1 Structure

43042-79-1 Structure
IdentificationBack Directory
[Name]

9ALPHA-11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER
[CAS]

43042-79-1
[Synonyms]

PGF2ALPHA-1-GLYCERYL ESTER
NWKPOVHSHWJQNI-OMVDPNNKSA-N
Prostaglandin F2α-1-glyceryl ester
PROSTAGLANDIN F2ALPHA-1-GLYCERYL ESTER
9ALPHA-11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER
Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, 2,3-dihydroxypropyl ester, (5Z,9α,11α,13E,15S)- (9CI)
[Molecular Formula]

C23H40O7
[MDL Number]

MFCD05863939
[MOL File]

43042-79-1.mol
[Molecular Weight]

428.56
Chemical PropertiesBack Directory
[solubility ]

DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 500 μg/ml
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H360
[Precautionary statements ]

P201-P202-P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P308+P313-P337+P313-P370+P378-P403+P235-P405-P501
Hazard InformationBack Directory
[Uses]

2-Arachidonoyl glycerol (2-AG; ) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in PG glyceryl ester formation. The biosynthesis of PGH, PGD, PGE, PGF, and thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of PGF2α-1-glyceryl ester has been investigated, little is known about its intrinsic biological activity.
[Definition]

ChEBI: Prostaglandin F2alpha 1-glyceryl ester is a 1-monoglyceride resulting from the condensation of the carboxy group of prostaglandin F2alpha with the 1-hydroxy group of glycerol. It has a role as a human metabolite. It is a 1-monoglyceride, an olefinic compound, a secondary alcohol, a prostaglandins Falpha and a pentol. It is functionally related to a prostaglandin F2alpha.
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