| Identification | Back Directory | [Name]
PU-24FCl | [CAS]
422508-46-1 | [Synonyms]
PU-24FCl
8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-2-fluoro-9-pent-4-ynylpurin-6-amine | [Molecular Formula]
C20H21ClFN5O3 | [MDL Number]
MFCD20527249 | [MOL File]
422508-46-1.mol | [Molecular Weight]
433.86 |
| Hazard Information | Back Directory | [Description]
PU24FCl is a specific inhibitor of tumor Hsp90. | [Uses]
PU24FCl is a specific inhibitor of Hsp90. PU24FCl exhibits wide-ranging anti-cancer activities. PU24FCl accumulates in tumors while being rapidly cleared from normal tissue[1]. | [IC 50]
HSP90 | [References]
[1] Vilenchik M, et, al. Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90. Chem Biol. 2004 Jun;11(6):787-97. DOI:10.1016/j.chembiol.2004.04.008 |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
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