| Identification | Back Directory | [Name]
5α-Cholestane-3β,6α-diol | [CAS]
41083-73-2 | [Synonyms]
6α-OHC
6-hydroxy Cholesterol
6α-hydroxy Cholesterol
5α-Cholestane-3β,6α-diol
6α-hydroxy-5α-cholestane
6α-hydroxy-5α-cholestanol
Cholestane-3,6-diol, (3β,5α,6α)-
6α hydroxy Cholesterol,6αhydroxy Cholesterol
6Α-HYDROXY-5Α-CHOLESTANE;6Α-HYDROXY-5Α-CHOLESTANOL | [Molecular Formula]
C27H48O2 | [MDL Number]
MFCD00201236 | [MOL File]
41083-73-2.mol | [Molecular Weight]
404.67 |
| Chemical Properties | Back Directory | [Boiling point ]
503.4±33.0 °C(Predicted) | [density ]
1.003±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 2 mg/ml; DMSO: 0.1 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml | [form ]
A crystalline solid | [pka]
14.79±0.70(Predicted) |
| Hazard Information | Back Directory | [Description]
6α-hydroxy Cholesterol is an oxysterol that increases superoxide anion production in SK-N-BE cells when used at concentrations of 50 and 100 μM.1 | [Uses]
6α-Hydroxy-5α-cholestanol is an analyte in a biochemical study determining a comprehesive method for extraction and quantitative analysis of sterols and secosteroids from human plasma. | [Definition]
ChEBI: 6alpha-hydroxycholestanol is a sterol that is cholestanol in which the hydrogen at the 6alpha position has been replaced by a hydroxy group. It is a 3beta-hydroxy steroid, a 6alpha-hydroxy steroid, a diol and a sterol. | [References]
1. Zarrouk, A., Nury, T., Samadi, M., et al. Effects of cholesterol oxides on cell death induction and calcium increase in human neuronal cells (SK-N-BE) and evaluation of the protective effects of docosahexaenoic acid (DHA; C22:6 n-3) Steroids 99(Pt B),238-247(2015). |
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Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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