| Identification | Back Directory | [Name]
GUANYL-CYS-OH | [CAS]
40454-21-5 | [Synonyms]
iqb-782
GUANYL-CYS-OH
GUANYL-L-CYSTEINE
n-amidinocysteine
n-guanyl-cysteine
N-Guanyl-L-cysteine
N-amidino-L-cysteine
N-ALPHA-GUANYL-L-CYSTEINE
n-(aminoiminomethyl)-l-cystein
N-(Aminoiminomethyl)-L-cysteine
n-guanidine-beta-mercaptoalanine
L-Cysteine, N-(aminoiminomethyl)-
(R)-2-Guanidino-3-mercaptopropanoic acid | [EINECS(EC#)]
254-925-1 | [Molecular Formula]
C4H9N3O2S | [MDL Number]
MFCD00672377 | [MOL File]
40454-21-5.mol | [Molecular Weight]
163.2 |
| Hazard Information | Back Directory | [Uses]
IQB-782 is a cysteine derivative. IQB-782 has inhibition for thrombin activatable fibrinolysis inhibitor (TAFI), with an Ki(app) of 0.14 μM. IQB-782 shows a potent mucolytic-expectorant activity[1][2]. | [References]
[1] Do YH, et al. Inhibition of thrombin activatable fibrinolysis inhibitor by cysteine derivatives. Thromb Res. 2005;116(3):265-71. DOI:10.1016/j.thromres.2004.12.023
[2] Moratalla R, et al. Pharmacological study of the new mucolytic drug N-guanyl-cysteine. Arzneimittelforschung. 1986 Jun;36(6):918-23. PMID:88747 |
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