| Identification | Back Directory | [Name]
N-(3-chloro-4-hydroxyphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide | [CAS]
397281-20-8 | [Synonyms]
EJMC-1
WAY-270599
N-(3-chloro-4-hydroxyphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide
Benz[cd]indole-6-sulfonamide, N-(3-chloro-4-hydroxyphenyl)-1,2-dihydro-2-oxo- | [Molecular Formula]
C17H11ClN2O4S | [MDL Number]
MFCD02916733 | [MOL File]
397281-20-8.mol | [Molecular Weight]
374.8 |
| Chemical Properties | Back Directory | [density ]
1.651±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (333.51 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [pka]
8.04±0.31(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
EJMC-1 is a moderately potent TNF-α inhibitor with an IC50 value of 42 μM[1]. | [storage]
Store at -20°C | [References]
[1] Deng X, et al. Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors. Front Chem. 2018 Apr 4;6:98. DOI:10.3389/fchem.2018.00098 |
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