| Identification | Back Directory | [Name]
ETHYL 2-AMINO-3-HYDROXYPROPANOATE HYDROCHLORIDE | [CAS]
3940-27-0 | [Synonyms]
NSC 29417
H-DL-Ser-OEt·HCl
H-DL-Serine ethyl ester HCl
DL-Serine Ethyl Ester Hydrochoride
DL-SERINE ETHYL ESTER HYDROCHLORIDE
ethyl2-amino-3-hydroxypropanoateHCl
H-DL-Serine ethyl ester hydrochloride
ETHYL 2-AMINO-3-HYDROXYPROPANOATE HYDROCHLORIDE
Ethyl 2-amino-3-hydroxypropanoate hydrochloride 98%
(D,L)-ethyl 2-amino-3-hydroxypropanoate hydrochloride
ETHYL 2-AMINO-3-HYDROXYPROPANOATE HYDROCHLORIDE USP/EP/BP | [Molecular Formula]
C5H12ClNO3 | [MDL Number]
MFCD00067544 | [MOL File]
3940-27-0.mol | [Molecular Weight]
169.61 |
| Hazard Information | Back Directory | [Uses]
H-DL-Serine ethyl ester HCl | [Synthesis]
1. 5.4 mL of thionyl chloride (about two drops) was slowly added dropwise to a 100 mL three-necked flask containing 40 mL of ethanol under an ice-water bath and mechanical stirring, and stirring was continued for 1 hr after completion of the dropwise addition.
2. 6.00 g (57 mmol) of L-serine was added to the above reaction system and the reaction was heated to reflux for 10 hours.
3. After completion of the reaction, the solvent was removed by distillation under reduced pressure to give 9.05 g of the white solid product L-serine ethyl ester hydrochloride (III) in 93.4% yield. | [References]
[1] Patent: CN105777611, 2016, A. Location in patent: Paragraph 0052; 0053 |
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