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ChemicalBook--->CAS DataBase List--->38451-63-7

38451-63-7

38451-63-7 Structure

38451-63-7 Structure
IdentificationBack Directory
[Name]

Asatone
[CAS]

38451-63-7
[Synonyms]

Asatone
Asatone USP/EP/BP
1,4-Ethanonaphthalene-6,10(4H)-dione, 1,4a,5,8a-tetrahydro-1,5,5,7,9,9-hexamethoxy-3,8a-di-2-propen-1-yl-, (1R,4S,4aS,8aS)-rel-
[Molecular Formula]

C24H32O8
[MOL File]

38451-63-7.mol
[Molecular Weight]

448.51
Chemical PropertiesBack Directory
[Boiling point ]

536.1±50.0 °C(Predicted)
[density ]

1.19±0.1 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Chemical Properties]

Blocky white crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from AsarumsieboldiiMiq.
[Uses]

Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways[1].
[Biological Activity]

Asatone, an active ingredient isolated from Asarum, has anti-inflammatory activity by activating NF-κB and downregulating p-MAPK (ERK, JNK and p38) pathways.
[target]

NF-κB

[storage]

4°C, protect from light
[References]

[1] Chang HY, et al. Asatone Prevents Acute Lung Injury by Reducing Expressions of NF-[Formula: see text]B, MAPK and Inflammatory Cytokines. Am J Chin Med. 2018;46(3):651-671. DOI:10.1142/S0192415X18500349
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