| Identification | Back Directory | [Name]
3'-Azido-3'-deoxy-N6,N6-dimethyladenosine | [CAS]
384334-64-9 | [Synonyms]
3'-Azido-3'-deoxy-N6-dimethyladenosine
3'-Azido-3'-deoxy-N6,N6-dimethyladenosine | [Molecular Formula]
C12H16N8O3 | [MOL File]
384334-64-9.mol | [Molecular Weight]
320.31 |
| Hazard Information | Back Directory | [Uses]
3’-Azido-3’-deoxy-N6,N6-dimethyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3’-Azido-3’-deoxy-N6,N6-dimethyladenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
|
| Company Name: |
T&W GROUP
|
| Tel: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.yuhua99.com/ShowSupplierProductsList1701258/0_EN.htm |
|