Identification | Back Directory | [Name]
8H-Phthalazino[1,2-b]quinazolin-8-one, 5-[[3-(dimethylamino)propyl]amino]- | [CAS]
379247-14-0 | [Synonyms]
BMH7 BMH-7 BMH 7 8H-Phthalazino[1,2-b]quinazolin-8-one, 5-[[3-(dimethylamino)propyl]amino]- | [Molecular Formula]
C20H21N5O | [MOL File]
379247-14-0.mol | [Molecular Weight]
347.41 |
Hazard Information | Back Directory | [Description]
BMH-7 is a p53 activator with potent antitumor activity. It regulates the p53 signaling pathway in bladder cancer cells. BMH-7 also induces apoptosis, changes cell size, and leads to cell death. BMH-7 is derived from quinazolinone, a small molecule that is able to activate the p53 tumor suppressor pathway. | [Uses]
Histamine H4 receptor antagonist-2 serves as a potent activator of p53, demonstrating significant antitumor efficacy. |
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BOC Sciences
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