Identification | Back Directory | [Name]
H-TYR-HIS-OH | [CAS]
3788-44-1 | [Synonyms]
YH H-TYR-HIS-OH L-Tyr-L-His-OH L-Histidine, L-tyrosyl- | [Molecular Formula]
C15H18N4O4 | [MDL Number]
MFCD00238237 | [MOL File]
3788-44-1.mol | [Molecular Weight]
318.33 |
Chemical Properties | Back Directory | [Melting point ]
270 °C | [Boiling point ]
763.4±60.0 °C(Predicted) | [density ]
1.421±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [pka]
2.83±0.10(Predicted) | [Sequence]
H-Tyr-His-OH |
Hazard Information | Back Directory | [Uses]
Tyrosylhistidine is a dipeptide consisting of tyrosine and histidine (Tyr-His). Tyrosylhistidine is an orally active antihypertensive peptide. Tyrosylhistidine reduces blood pressure in mice in a model of spontaneous hypertension[1]. | [Definition]
ChEBI: Tyr-His is a dipeptide formed from L-tyrosine and L-histidine residues. It has a role as a metabolite. It is functionally related to a L-tyrosine and a L-histidine. | [References]
[1] Suetsuna K, et al. Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats. J Nutr Biochem. 2004 May;15(5):267-72. DOI:10.1016/j.jnutbio.2003.11.004 |
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