| Identification | Back Directory | [Name]
ZQ-16 | [CAS]
376616-73-8 | [Synonyms]
ZQ-16
2-HTP
ZQ-16 >=98% (HPLC)
2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone
4(3H)-Pyrimidinone, 2-(hexylthio)-6-hydroxy- | [Molecular Formula]
C10H16N2O2S | [MOL File]
376616-73-8.mol | [Molecular Weight]
228.31 |
| Hazard Information | Back Directory | [Uses]
ZQ 16, is a potent and selective agonist for medium-chain free fatty acid receptor GPR84 (G protein-coupled receptor 84). It activates GPR84-mediated calcium mobilization, inhibits cAMP accumulation, phosphorylation of ERK1/2, receptor desensitization and internalization, and receptor-β-arrestin interaction. | [Biological Activity]
ZQ-16 is a potent and selective agonist for medium-chain free fatty acid receptor GPR84 (G protein-coupled receptor 84). ZQ-16 activates GPR84-mediated calcium mobilizationinhibition of cAMP accumulationphosphorylation of ERK1/2receptor desensitization and internalizationand receptor-β-arrestin interaction. |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|