Identification | Back Directory | [Name]
3,8-Dihydroxy-1,9-dimethyl-6-(1-methyl-1-propenyl)-11H-dibenzo[b,e][1,4]dioxepin-11-one | [CAS]
36587-59-4 | [Synonyms]
Unguinol 3,8-Dihydroxy-1,9-dimethyl-6-(1-methyl-1-propenyl)-11H-dibenzo[b,e][1,4]dioxepin-11-one | [Molecular Formula]
C19H18O5 | [MDL Number]
MFCD26961081 | [MOL File]
36587-59-4.mol | [Molecular Weight]
326.34 |
Chemical Properties | Back Directory | [Boiling point ]
552.2±50.0 °C(Predicted) | [density ]
1.291±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
A solid | [pka]
7.93±0.20(Predicted) |
Hazard Information | Back Directory | [Uses]
Unguinol is a depsidone originally isolated from A. unguis. It is an inhibitor of pyruvate phosphate dikinase (PPDK; IC50=42.3 μM). It inhibits the growth of plants utilizing C4, but not C3, carbon fixation. Unguinol also inhibits the growth of the bacteria S. aureus and V. harveyi (GI50s=8.7 and 69.5 μM, respectively) and H460, MCF-7, and SF-268 cancer cells (GI50s=28.2, 50.8, and 44.3 μM, respectively). | [storage]
Store at -20°C | [References]
[1] Stodola, et al. New depsidone from Aspergillus unguis. Phytochemistry 11(6), 2107-2108 (1972). |
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AstaTech, Inc
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(215) 785 3197 |
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www.astatechinc.com |
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