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ChemicalBook--->CAS DataBase List--->359436-59-2

359436-59-2

359436-59-2 Structure

359436-59-2 Structure
IdentificationBack Directory
[Name]

4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid
[CAS]

359436-59-2
[Synonyms]

Mal-?C2-cyclohexylcarboxyl-hydrazide TFA
4-(MaleiMidoMethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid Salt
4-[(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)Methyl]cyclohexanecarboxylic Acid Hydrazide, 2,2,2-Trifluoroacetate
Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, hydrazide, 2,2,2-trifluoroacetate (1:1)
[Molecular Formula]

C14H18F3N3O5
[MOL File]

359436-59-2.mol
[Molecular Weight]

365.305
Chemical PropertiesBack Directory
[Melting point ]

>210?C (dec.)
[storage temp. ]

-20°C Freezer
[solubility ]

Acetontrile (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
Hazard InformationBack Directory
[Chemical Properties]

White to Off-White Solid
[Uses]

Mal-?C2-cyclohexylcarboxyl-hydrazide (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

Alkyl-Chain
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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