| Identification | Back Directory | [Name]
Isobutanesulfonyl chloride | [CAS]
35432-36-1 | [Synonyms]
Isobutylsulfonyl chloride
Isobutanesulfonyl chloride
Isobutanesulfonyl chloride 97%
ISOBUTANESULFONYL CHLORIDE 97
2-Methylpropane-1-sulfonyl chloride
2-Methyl-1-propanesulfonyl chloride
1-Propanesulfonylchloride, 2-methyl-
Isobutanesulfonyl chloride ISO 9001：2015 REACH | [Molecular Formula]
C4H9ClO2S | [MDL Number]
MFCD07369800 | [MOL File]
35432-36-1.mol | [Molecular Weight]
156.63 |
| Chemical Properties | Back Directory | [Melting point ]
95 °C(Solv: pentane (109-66-0)) | [Boiling point ]
190°C | [density ]
1.200 g/mL at 25 °C(lit.) | [refractive index ]
n20/D 1.454(lit.)
| [Fp ]
190 °F
| [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
Liquid | [color ]
Colorless | [Sensitive ]
Moisture Sensitive |
| Hazard Information | Back Directory | [Synthesis]
Under nitrogen protection, 2-methyl-1-propanethiol (200 mg, 2.22 mmol) was dissolved in acetonitrile and cooled to 0 °C. N-chlorosuccinimide (561 mg, 5.5 mmol) and sulfonyl chloride (0.45 ml, 5.5 mmol) were added sequentially. The reaction mixture was kept stirred at 0 °C for 3 hours. After completion of the reaction, it was diluted with saturated sodium bicarbonate solution and extracted with ethyl acetate. The organic layers were combined, washed with saturated brine and dried over anhydrous magnesium sulfate. The solvent was concentrated under reduced pressure to give 2-methylpropanesulfonyl chloride (293 mg, 95% yield). | [References]
[1] Patent: WO2004/31139, 2004, A1. Location in patent: Page 19
[2] Journal fuer Praktische Chemie (Leipzig), 1979, vol. 321, p. 107 - 111
[3] Patent: US2009/215775, 2009, A1 |
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