123-38-6

292638-85-8

35351-35-0

Palladium(II) acetate [Pd(OAc)2] (0.2 mmol), H4PMo11V1O40 (15 μmol), cerium chloride heptahydrate (CeCl3-7H2O) (0.2 mmol), methanol (30 mmol), and acetic acid (4.5 mL) were added sequentially to the reactor. The reaction mixture was heated to 70 °C. A mixture of methyl acrylate (1 mmol), propionaldehyde (6 mmol) and acetic acid (0.5 mL) was added dropwise to the reaction system using a syringe pump at a rate of 5 μL/min under an oxygen atmosphere of 1 atm (0.1 MPa) for 8 hours. Upon completion of the reaction, the reaction mixture was analyzed by gas chromatography and the yield of methyl 5-methyl-3-furancarboxylate was measured to be 90%.