| Identification | Back Directory | [Name]
3-BROMOISOQUINOLINE | [CAS]
34784-02-6 | [Synonyms]
3-BROMOISOQUINOLINE
Isoquinoline, 3-bromo-
3-BROMOISOQUINOLINE 97%
3-Bromoisoquinoline ,99%
3-Bromo-2-azanaphthalene
3-BROMOISOQUINOLINE ISO 9001：2015 REACH | [Molecular Formula]
C9H6BrN | [MDL Number]
MFCD00234479 | [MOL File]
34784-02-6.mol | [Molecular Weight]
208.05 |
| Chemical Properties | Back Directory | [Melting point ]
63-64 °C | [Boiling point ]
316.3±15.0 °C(Predicted) | [density ]
1.564±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
solid | [pka]
1.84±0.30(Predicted) | [Appearance]
White to light brown Solid |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow powder | [Synthesis]
To a stirred solution of isoquinoline (24 g, 186 mmol) in acetic acid (50 mL) was slowly added N-bromosuccinimide (NBS, 36.2 g, 204.6 mmol) at room temperature. The reaction mixture was heated to 100 °C and kept at this temperature for the reaction overnight. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by fast column chromatography (eluent: 5% ethyl acetate/hexane) to give 3-bromoisoquinoline (9.2 g, 23.8% yield) as an oil. | [References]
[1] Patent: US2013/178457, 2013, A1. Location in patent: Paragraph 0219 |
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