Identification | Back Directory | [Name]
(5E)-1-(2-ethylphenyl)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione | [CAS]
347397-83-5 | [Synonyms]
cp028 Compound028 Compound-028 Compound 028 (5E)-1-(2-ethylphenyl)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione (5Z)-1-(2-ethylphenyl)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione | [Molecular Formula]
C23H17FN2O4 | [MOL File]
347397-83-5.mol | [Molecular Weight]
404.39 |
Hazard Information | Back Directory | [Description]
cp028 is an inhibitor of pre-mRNA splicing in vitro. | [Uses]
cp028 is a potent pre-mRNA splicing inhibitor. cp028 inhibits splicing in HeLa nuclear extract with an IC50 value of 54 μM[1]. | [References]
[1] Sidarovich A, et al. Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. Elife. 2017 Mar 16;6:e23533. DOI:10.7554/eLife.23533 |
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