| Identification | Back Directory | [Name]
VANDETANIB | [CAS]
338992-00-0 | [Synonyms]
HSDB 8198
VANDETANIB FUMARATE
(4-BROMO-2-FLUORO-PHENYL)-[6-METHOXY-7-(1-METHYL-PIPERIDIN-4-YLMETHOXY)-QUINAZOLIN-4-YL]-AMINE | [Molecular Formula]
C22H24BrFN4O2 | [MDL Number]
MFCD07772346 | [MOL File]
338992-00-0.mol |
| Hazard Information | Back Directory | [Uses]
Treatment of non-small cell lung cancer and other solid tumors. | [Definition]
ChEBI: Vandetanib is a quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease. It has a role as a tyrosine kinase inhibitor and an antineoplastic agent. It is an aromatic ether, a secondary amine, a member of quinazolines, a member of piperidines, an organobromine compound and an organofluorine compound. | [Brand name]
Zactima (AstraZeneca). |
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