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ChemicalBook--->CAS DataBase List--->330461-34-2

330461-34-2

330461-34-2 Structure

330461-34-2 Structure
IdentificationBack Directory
[Name]

DVR01
[CAS]

330461-34-2
[Synonyms]

DVR01
DVR-01
DVR 01
3-(Azepan-1-ylsulfonyl)-N-benzyl-4-chlorobenzamide
[Molecular Formula]

C20H23ClN2O3S
[MOL File]

330461-34-2.mol
[Molecular Weight]

406.93
Hazard InformationBack Directory
[Description]

DVR-01 is a potent HBV capsid inhibitor.
[Uses]

DVR-01 is a HBV inhibitor with EC50 values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively. DVR-01 shows antiviral activity against drug-resistant HBV mutants with EC50s of 2.403-3.273 μM. DVR-01 can be used for the research of HBV infection and related diseases[1].
[References]

[1] Campagna MR, et al. Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids. J Virol. 2013 Jun;87(12):6931-42. DOI:10.1128/JVI.00582-13
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