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ChemicalBook--->CAS DataBase List--->329306-46-9

329306-46-9

329306-46-9 Structure

329306-46-9 Structure
IdentificationBack Directory
[Name]

RQIKIWFQNRRMKWKK
[CAS]

329306-46-9
[Synonyms]

DT-5
PENETRATIN
RQIKIWFQNRRMKWKK
ANTENNAPEDIA PEPTIDE
H-RQIKIWFQNRRMKWKK-OH
H2N-RQIKIWFQNRRMKWKK-OH
DT-3 trifluoroacetate salt
DROSOPHILA ANTENNAPEDIA HOMEO-DOMAIN (43-58)
(DEFORMED)(CEPHALOTHORAX)(HOMEOBOX) FRAGMENT
ARG-GLN-ILE-LYS-ILE-TRP-PHE-GLN-ASN-ARG-ARG-MET-LYS-TRP-LYS-LYS
ARG-GLN-ILE-LYS-ILE-TRP-PHE-GLN-ASN-ARG-ARG-MET-LYS-TRP-LYS-LYS-OH
[Molecular Formula]

C152H258N52O28S
[MDL Number]

MFCD04974159
[MOL File]

329306-46-9.mol
[Molecular Weight]

3294.07
Chemical PropertiesBack Directory
[density ]

1.43±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
Hazard InformationBack Directory
[Uses]

DT-3 is a membrane-permeable protein kinase G Iα (PKG Iα) inhibitory peptide and shows pharmacological blockade of the cGMP-PKG signalling[1].
[References]

[1] Shinichi Takahashi, et al. Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. J Physiol. 2008 Sep 1;586(17):4209-23. DOI:10.1113/jphysiol.2008.156083
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