| Identification | Back Directory | [Name]
7-Bromo-2-iodo-9,9-dimethyl-9H-fluorene | [CAS]
319906-45-1 | [Synonyms]
2-Bromo-7-iodo-9,9-d
2-Bromo-7-iodo-9,9-dimethyl-fluoren
2-Bromo-7-iodo-9,9-dimethylfluorene
7-Bromo-2-iodo-9,9-dimethyl-9H-fluorene
2-Bromo-7-iodo-9,9-dimethyl-9H-fluorene
9H-Fluorene, 2-bromo-7-iodo-9,9-dimethyl- | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C15H12BrI | [MDL Number]
MFCD12024277 | [MOL File]
319906-45-1.mol | [Molecular Weight]
399.06 |
| Chemical Properties | Back Directory | [Boiling point ]
424.2±38.0 °C(Predicted) | [density ]
1.773 | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Synthesis]
Synthesis of Intermediate 1: 30.27 g (110.8 mmol) of 9,9-dimethyl-2-bromofluorene, 16.9 g (66.5 mmol) of iodine (I2) and 15.2 g (66.5 mmol) of periodate (H5IO6) were dissolved in acetic acid (AcOH). To this solution, dilute aqueous sulfuric acid (H2SO4) was slowly added dropwise and the reaction was stirred at 50°C for 5 hours. Upon completion of the reaction, deionized water was added to the reaction mixture and a solid precipitate was precipitated. The precipitate was collected by filtration to give 37.6 g of intermediate 1 in 85% yield. The resulting compound was structurally confirmed by high resolution mass spectrometry (HR-MS). | [References]
[1] Angewandte Chemie - International Edition, 2016, vol. 55, # 44, p. 13724 - 13728
[2] Angew. Chem., 2016, vol. 128, p. 13928 - 13932,5
[3] Patent: EP2292603, 2011, A1. Location in patent: Page/Page column 24
[4] Patent: EP2738166, 2014, A1. Location in patent: Paragraph 0153-0154
[5] Patent: EP2762478, 2014, A1. Location in patent: Paragraph 0179; 0180 |
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