| Identification | Back Directory | [Name]
Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate | [CAS]
30062-34-1 | [Synonyms]
methyl 6-hydroxypicolinate
6-Methoxycarbonyl-2-pyridone
methyl 6-oxo-1H-pyridine-2-carboxylate
methyl 6-hydroxypicolinate hydrochloride
Methyl 6-oxo-1,6-dihydropyridine-2-carboxylate
2-Pyridinecarboxylic acid, 1,6-dihydro-6-oxo-, methyl ester | [Molecular Formula]
C7H7NO3 | [MDL Number]
MFCD17015470 | [MOL File]
30062-34-1.mol | [Molecular Weight]
153.14 |
| Chemical Properties | Back Directory | [Melting point ]
109-110 °C | [Boiling point ]
367.6±42.0 °C(Predicted) | [density ]
1.263±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
8.83±0.10(Predicted) | [Appearance]
White to off-white Solid | [InChI]
InChI=1S/C7H7NO3/c1-11-7(10)5-3-2-4-6(9)8-5/h2-4H,1H3,(H,8,9) | [InChIKey]
GJLWQAUHCDNAEK-UHFFFAOYSA-N | [SMILES]
C1(C(OC)=O)NC(=O)C=CC=1 |
| Hazard Information | Back Directory | [Synthesis]
Step 1: Synthesis of methyl 6-hydroxypyridine-2-carboxylate. 6-Hydroxypyridine-2-carboxylic acid (13.0 g, 93.5 mmol) was dissolved in methanol (150 mL) at room temperature and a dioxane solution of 4N HCl (10 mL) was slowly added. The reaction mixture was stirred at room temperature for 48 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure to afford methyl 6-hydroxypyridine-2-carboxylate (13 g, 90% yield) as a white solid. | [References]
[1] Patent: WO2004/37808, 2004, A1. Location in patent: Page 19-20
[2] Patent: WO2014/154727, 2014, A1. Location in patent: Page/Page column 38; 52
[3] Patent: US2014/296239, 2014, A1. Location in patent: Paragraph 0097; 0098
[4] Patent: WO2014/154726, 2014, A1. Location in patent: Page/Page column 38-39
[5] Patent: US2014/296296, 2014, A1. Location in patent: Paragraph 0106; 0107 |
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