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ChemicalBook--->CAS DataBase List--->295325-62-1

295325-62-1

295325-62-1 Structure

295325-62-1 Structure
IdentificationBack Directory
[Name]

(S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID
[CAS]

295325-62-1
[Synonyms]

MNI-caged-L-glutamat
MNI-CAGED-L-GLUTAMATE
GXIDBZKXGUNITQ-VIFPVBQESA-N
(S)-2-Amino-5-(4-methoxy-7-nitro-1-indolinyl)-5-oxopentanoic Acid
(S)-2-Amino-5-(4-methoxy-7-nitroindolin-1-yl)-5-oxopentanoic acid
(S)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoicacid
(2S)-2-amino-5-(4-methoxy-7-nitro-2,3-dihydroindol-1-yl)-5-oxopentanoic acid
(S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID
1H-Indole-1-pentanoic acid, α-amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-, (αS)-
[Molecular Formula]

C14H17N3O6
[MDL Number]

MFCD06798370
[MOL File]

295325-62-1.mol
[Molecular Weight]

323.3
Chemical PropertiesBack Directory
[Melting point ]

>160°C (dec.)
[storage temp. ]

Store at -20°C
[solubility ]

Methanol (Slightly), Water (Slightly)
[form ]

Solid
[color ]

Light Yellow
[Water Solubility ]

Soluble to 50 mM in water with gentle warming
Hazard InformationBack Directory
[Uses]

MNI-caged-L-glutamate, is a new caged neuroactive amino acid, that use 4-methoxy-7-nitroindolinyl- (MNI) group to make caged ligands specific for glutamate receptor sub-types. MNI-caged-L-glutamate, rapidly release glutamate when photolysed.
[Biological Activity]

Caged glutamate that rapidly and efficiently releases glutamate when photolysed (300-380 nm excitation). Water-soluble, highly resistant to hydrolysis, stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). 2.5-fold more efficient at releasing L-glutamate than NI-caged L-glutamate.
[storage]

Store at -20°C
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