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ChemicalBook--->CAS DataBase List--->2924425-63-6

2924425-63-6

2924425-63-6 Structure

2924425-63-6 Structure
IdentificationBack Directory
[Name]

PB131
[CAS]

2924425-63-6
[Synonyms]

PB131
[Molecular Formula]

C16H16FN3O2
[MOL File]

2924425-63-6.mol
[Molecular Weight]

301.32
Chemical PropertiesBack Directory
[density ]

1.343±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

8.480±0.10(predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

PB131 is a selective and brain-permeable HDAC6 inhibitor with high binding affinity (IC50: 1.8 nM). PB131 has potent anti-inflammatory activity. PB131 can be used for research of inflammation, especially neuroinflammation[1].
[References]

[1] Liu G, et al. Design, synthesis, and anti-inflammatory activity characterization of novel brain-permeable HDAC6 inhibitors. Eur J Med Chem. 2023 Jun 5;254:115327. DOI:10.1016/j.ejmech.2023.115327
2924425-63-6 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 021-13816613772 13816613772
Website: www.yuhua99.com/ShowSupplierProductsList16976/0_EN.htm
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Tags:2924425-63-6 Related Product Information

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