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ChemicalBook--->CAS DataBase List--->2921944-77-4

2921944-77-4

2921944-77-4 Structure

2921944-77-4 Structure
IdentificationBack Directory
[Name]

UCM-13369
[CAS]

2921944-77-4
[Synonyms]

UCM-13369
Hazard InformationBack Directory
[Uses]

UCM-13369 (Compound 4b) is a NPM1 inhibitor. UCM-13369 downregulates the pathway associated with mutant NPM1 C+, and specifically recognizes the C-end DNA-binding domain of NPM1 C+. UCM-13369 induces apoptosis in AML cell lines and primary cells, that can be used for the research of AML[1].
[References]

[1] Algar S, et al. Cancer-Stem-Cell Phenotype-Guided Discovery of a Microbiota-Inspired Synthetic Compound Targeting NPM1 for Leukemia. JACS Au. 2024.
2921944-77-4 suppliers list
Company Name: Wuhan Jingkangen Biomedical Technology Co., Ltd  
Tel: 13720134139 086-15871494362 13720134139
Website: https://www.jknbiochem.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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