Chemical Properties | Back Directory | [Boiling point ]
434.4±55.0 °C(predicted) | [density ]
1.412±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
6.61±0.20(predicted) |
Hazard Information | Back Directory | [Uses]
EBOV-IN-4 (compound 12), a benzothiazepine, is a potent Ebola virus (EBOV) inhibitor with 64.9% inhibitory for EBOV-GP-pseudotype virus (pEBOV) with 10 μM. EBOV-IN-4 is inactive with ASFV[1]. | [IC 50]
EBOV | [References]
[1] Fátima Lasala, et al. Identification of potential inhibitors of protein-protein interaction useful to fight against Ebola and other highly pathogenic viruses. Antiviral Res. 2021 Feb:186:105011. DOI:10.1016/j.antiviral.2021.105011 |
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