Identification | Back Directory | [Name]
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol | [CAS]
2891774-71-1 | [Synonyms]
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol | [Molecular Formula]
C31H30FN3O6 | [MOL File]
2891774-71-1.mol | [Molecular Weight]
559.59 |
Chemical Properties | Back Directory | [Boiling point ]
970.909±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.568±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
11.179±0.40(predicted) |
Hazard Information | Back Directory | [Uses]
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45) is a camptothecin compound that can inhibit cell proliferation, with an IC50 of 2.92 ng/mL for MDA?MB?468 cells. Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol can be used for the research of cancer[1]. | [IC 50]
Camptothecins | [References]
[1] QD Wen, et, al. Novel camptothecin compound and preparation method and application thereof. CN115557962A. |
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