Chemical Properties | Back Directory | [Boiling point ]
512.6±60.0 °C(predicted) | [density ]
1.494±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
3.95±0.10(predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
TAS2R14 agonist-2 (compound 28.1) is a potent and selective TAS2R14 inhibitor with an EC50 value of 72 nM[1]. | [References]
[1] Waterloo L, et al. Discovery of 2-Aminopyrimidines as Potent Agonists for the Bitter Taste Receptor TAS2R14. J Med Chem. 2023 Mar 9;66(5):3499-3521. DOI:10.1021/acs.jmedchem.2c01997 |
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