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ChemicalBook--->CAS DataBase List--->28789-35-7

28789-35-7

28789-35-7 Structure

28789-35-7 Structure
IdentificationBack Directory
[Name]

NORDIHYDROCAPSAICIN
[CAS]

28789-35-7
[Synonyms]

Norhydrocapsaicin
Nordihydrocapsaic
NORDIHYDROCAPSAICIN
NORDIHYDROCAPSAICIN USP/EP/BP
N-(4-Hydroxy-3-methoxybenzyl)-7-methyloctanamide
N-[(4-Hydroxy-3-methoxyphenyl)methyl]-7-methyl-octanamide
Octanamide,N-[(4-hydroxy-3-methoxyphenyl)methyl]-7-methyl-
[Molecular Formula]

C17H27NO3
[MDL Number]

MFCD06796690
[MOL File]

28789-35-7.mol
[Molecular Weight]

293.4
Chemical PropertiesBack Directory
[Boiling point ]

487.0±35.0 °C(Predicted)
[density ]

1.036±0.06 g/cm3 (20 ºC 760 Torr)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

Chloroform: soluble; DMSO: soluble
[form ]

A crystalline solid
[pka]

9.76±0.20(Predicted)
[color ]

Light brown to gray
[LogP]

3.046 (est)
[EPA Substance Registry System]

Nordihydrocapsaicin (28789-35-7)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[HS Code ]

2939800000
Hazard InformationBack Directory
[Uses]

Nordihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers.
[Definition]

ChEBI: Nordihydrocapsaicin is a member of methoxybenzenes and a member of phenols.
[in vivo]

Nordihydrocapsaicin (0.1-0.2% CAPs (10 mg/kg BW), p.o., daily for 8 weeks) prevents low-fat-high carbohydrate diet and high-fat diet-induced obesity by regulating the NADPH oxidase and Nrf2 pathways in rats[4].

Animal Model:Wistar rats [4]
Dosage:0.1%–0.2% CAPs (10 mg/kg BW)
Administration:p.o., daily for 8 weeks
Result:Caused a 32% and 37% reduction for HSD and 16% and 18% reduction for HFD in serum and liver MDA concentrations and elevation in serum TAC by 163% and 54% in the HSD- and HFD-fed rats (P<0.001), respectively.
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