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IdentificationBack Directory
[Name]

(R)-CSN5i-3
[CAS]

NoCAS
[Synonyms]

(R)-CSN5i-3
[Molecular Formula]

C28H29F2N5O2
[MOL File]

2863607-74-1.mol
[Molecular Weight]

505.56
Chemical PropertiesBack Directory
[Boiling point ]

666.5±55.0 °C(predicted)
[density ]

1.35±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

12.66±0.70(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

(R)-CSN5i-3 is the (R)-enantiomer of CSN5i-3. CSN5i-3 is a potent, selective and orally available inhibitor of CSN5[1].
[References]

[1] Schlierf A, et al. Targeted inhibition of the COP9 signalosome for treatment of cancer. Nat Commun. 2016 Oct 24;7:13166. DOI:10.1038/ncomms13166
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