Identification | Back Directory | [Name]
9H-Imidazo[5,1-f]purine, 2-(4-cyclopropyl-6-methoxy-5-pyrimidinyl)-9-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]- | [CAS]
2857051-98-8 | [Synonyms]
9H-Imidazo[5,1-f]purine, 2-(4-cyclopropyl-6-methoxy-5-pyrimidinyl)-9-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]- | [Molecular Formula]
C27H22F3N9O | [MOL File]
2857051-98-8.mol | [Molecular Weight]
545.52 |
Hazard Information | Back Directory | [Uses]
USP1-IN-10 (compound 2) is a potent tricyclic USP1 inhibitor with an IC50 of 7.6 nM. USP1-IN-10 inhibits MDA-MB-436 viability (IC50=21.58 nM). USP1-IN-10 has the potential for cancers research[1]. | [IC 50]
USP1: 7.6 nM (IC50) | [References]
[1] Bin Liu, et al. Tricyclic usp1 inhibitor and use thereof. WO2022228399A1. |
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