Identification | Back Directory | [Name]
agathisflavone | [CAS]
28441-98-7 | [Synonyms]
8'-Biapigenin agathisflavone 6,8'-Biapigenin 6,8''-Bi[4',5,7-trihydroxyflavone] 4',4''',5,5'',7,7''-Hexahydroxy-6,8''-biflavone 5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-6,8'-bi[4H-1-benzopyran]-4,4'-dione [6,8'-Bi-4H-1-benzopyran]-4,4'-dione, 5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)- | [Molecular Formula]
C30H18O10 | [MOL File]
28441-98-7.mol | [Molecular Weight]
538.46 |
Chemical Properties | Back Directory | [Boiling point ]
929.1±65.0 °C(Predicted) | [density ]
1.656±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
5.41±0.40(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Uses]
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats[1][2][3]. | [Definition]
ChEBI: A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-6 and C-8 of the two chromene rings. | [References]
[1] Islam MT, et, al. Agathisflavone: Botanical sources, therapeutic promises, and molecular docking study. IUBMB Life. 2019 Sep;71(9):1192-1200. DOI:10.1002/iub.2053 [2] Freitas CS, et, al. Agathisflavone, a Biflavonoid from Anacardium occidentale L., Inhibits Influenza Virus Neuraminidase. Curr Top Med Chem. 2020;20(2):111-120. DOI:10.2174/1568026620666191219150738 [3] Nascimento RP, et, al. Agathisflavone as a Single Therapy or in Association With Mesenchymal Stem Cells Improves Tissue Repair in a Spinal Cord Injury Model in Rats. Front Pharmacol. 2022 Apr 5;13:858190. DOI:10.3389/fphar.2022.858190 |
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