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ChemicalBook--->CAS DataBase List--->28441-98-7

28441-98-7

28441-98-7 Structure

28441-98-7 Structure
IdentificationBack Directory
[Name]

agathisflavone
[CAS]

28441-98-7
[Synonyms]

8'-Biapigenin
agathisflavone
6,8'-Biapigenin
6,8''-Bi[4',5,7-trihydroxyflavone]
4',4''',5,5'',7,7''-Hexahydroxy-6,8''-biflavone
5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-6,8'-bi[4H-1-benzopyran]-4,4'-dione
[6,8'-Bi-4H-1-benzopyran]-4,4'-dione, 5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-
[Molecular Formula]

C30H18O10
[MOL File]

28441-98-7.mol
[Molecular Weight]

538.46
Chemical PropertiesBack Directory
[Boiling point ]

929.1±65.0 °C(Predicted)
[density ]

1.656±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

5.41±0.40(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats[1][2][3].
[Definition]

ChEBI: A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-6 and C-8 of the two chromene rings.
[References]

[1] Islam MT, et, al. Agathisflavone: Botanical sources, therapeutic promises, and molecular docking study. IUBMB Life. 2019 Sep;71(9):1192-1200. DOI:10.1002/iub.2053
[2] Freitas CS, et, al. Agathisflavone, a Biflavonoid from Anacardium occidentale L., Inhibits Influenza Virus Neuraminidase. Curr Top Med Chem. 2020;20(2):111-120. DOI:10.2174/1568026620666191219150738
[3] Nascimento RP, et, al. Agathisflavone as a Single Therapy or in Association With Mesenchymal Stem Cells Improves Tissue Repair in a Spinal Cord Injury Model in Rats. Front Pharmacol. 2022 Apr 5;13:858190. DOI:10.3389/fphar.2022.858190
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